Computer Configuration > Administrative Templates > Microsoft Edge > Identity and sign-in
Both
HKLM\Software\Policies\Microsoft\Edge
Allows Microsoft Edge to switch to the appropriate profile when navigating to a site that matches an entry on the IE mode site list. Only sites that specify IE mode or Edge mode will be switched to the work or school profile. If you enable or don't configure this policy, navigations to URLs matching a site on the IE mode site list will switch to the most recently used work or school profile if one exists. If you disable this policy, navigations to URLs matching a site on the IE mode site list will remain in the current browser profile.