Computer Configuration > Administrative Templates > Microsoft Edge
Both
HKLM\Software\Policies\Microsoft\Edge
This policy lets you configure the Mouse Gesture feature in Microsoft Edge. This feature provides an easy way for users to complete tasks like scroll forward or backward, open new tab, refresh page, etc. They can finish a task by pressing and holding the mouse right button to draw certain patterns on a webpage, instead of clicking the buttons or using keyboard shortcuts. If you enable or don't configure this policy, you can use the Mouse Gesture feature on Microsoft Edge to start using this feature. If you disable this policy, you can't use the Mouse Gesture feature in Microsoft Edge.