Computer Configuration > Administrative Templates > Microsoft Edge > Content settings
Both
HKLM\Software\Policies\Microsoft\Edge
Allows you to set a list of site url patterns that specify sites for which advanced JavaScript optimizations are enabled. For detailed information on valid site url patterns, please see https://go.microsoft.com/fwlink/?linkid=2095322. Wildcards, *, are allowed. JavaScript optimization policy exceptions will only be enforced at a site granularity (eTLD+1). A policy set for only subdomain.contoso.com will not correctly apply to contoso.com or subdomain.contoso.com since they both resolve to the same eTLD+1 (contoso.com) for which there is no policy. In this case, policy must be set on contoso.com to apply correctly for both contoso.com and subdomain.contoso.com. This policy applies on a frame-by-frame basis and not based on top level origin url alone, so e.g. if contoso.com is listed in the 'JavaScriptOptimizerAllowedForSites' (Allow JavaScript optimization on these sites) policy but contoso.com loads a frame containing fabrikam.com then contoso.com will have JavaScript optimizations enabled, but fabrikam.com will use the policy from 'DefaultJavaScriptOptimizerSetting' (Control use of JavaScript optimizers), if set, or default to JavaScript optimizations enabled. Blocklist entries have higher priority than allowlist entries, which in turn have higher priority than the configured default value. If you don't configure this policy for a site then the policy from 'DefaultJavaScriptOptimizerSetting' applies to the site, if set, otherwise Javascript optimization is enabled for the site. Example value: [*.]example.edu