Computer Configuration > Administrative Templates > Microsoft Edge - Default Settings (users can override) > Startup, home page and new tab page
Both
HKLM\Software\Policies\Microsoft\Edge\Recommended
Configures the default home page URL in Microsoft Edge. The home page is the page opened by the Home button. The pages that open on startup are controlled by the 'RestoreOnStartup' (Action to take on Microsoft Edge startup) policies. You can either set a URL here or set the home page to open the new tab page 'edge://newtab'. By default, the Home button will open the new tab page (as configured by the user or with the policy 'NewTabPageLocation' (Configure the new tab page URL)), and the user will be able to choose between the URL configured by this policy and the new tab page. If you enable this policy, users can't change their home page URL, but they can choose the behavior for the Home button to open either the set URL or the new tab page. If you wish to enforce the usage of the set URL you must also configure 'HomepageIsNewTabPage' (Set the new tab page as the home page)=Disabled. If you disable or don't configure this policy, users can choose their own home page, as long as the 'HomepageIsNewTabPage' policy isn't enabled. This policy is available only on Windows instances that are joined to a Microsoft Active Directory domain, joined to Microsoft Azure Active Directory, or instances that enrolled for device management. On macOS, this policy is available only on instances that are managed via MDM or joined to a domain via MCX. Example value: https://www.contoso.com