Computer Configuration > Administrative Templates > Microsoft Edge
Both
HKLM\Software\Policies\Microsoft\Edge
Specifies whether the AutoLaunch Protocols component should be enabled. This component allows Microsoft to provide a list similar to that of the 'AutoLaunchProtocolsFromOrigins' (Define a list of protocols that can launch an external application from listed origins without prompting the user) policy, allowing certain external protocols to launch without prompt or blocking certain protocols (on specified origins). By default, this component is enabled. If you enable or don't configure this policy, the AutoLaunch Protocols component is enabled. If you disable this policy, the AutoLaunch Protocols component is disabled.