Computer Configuration > Administrative Templates > Google Chrome > First-Party Sets Settings
Both
HKLM\Software\Policies\Google\Chrome
This policy is provided as a way to opt-out of the First-Party Sets feature. When this policy is unset or set to Enabled, the First-Party Sets feature is enabled. When this policy is set to Disabled, the First-Party Sets feature is disabled. It controls whether Chrome supports First-Party Sets related integrations. This is the equivalent of the RelatedWebsiteSetsEnabled policy. Either policy may be used, but this one will be deprecated soon so the RelatedWebsiteSetsEnabled policy is preferred. They both have the same effect on the browser's behavior.